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MRP6 (ABCC6) (NM_001171) Human Tagged ORF Clone
CAT＃: RC211938
- TrueORF®
ABCC6 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1
ORF Plasmid: tGFP
"NM_001171" in other vectors (6)
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CNY 15,424.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ABC34; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC211938 representing NM_001171
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCGCGCCTGCTGAGCCCTGCGCGGGGCAGGGGGTCTGGAACCAGACAGAGCCTGAACCTGCCGCCA CCAGCCTGCTGAGCCTGTGCTTCCTGAGAACAGCAGGGGTCTGGGTACCCCCCATGTACCTCTGGGTCCT TGGTCCCATCTACCTCCTCTTCATCCACCACCATGGCCGGGGCTACCTCCGGATGTCCCCACTCTTCAAA GCCAAGATGGTGCTTGGATTCGCCCTCATAGTCCTGTGTACCTCCAGCGTGGCTGTCGCTCTTTGGAAAA TCCAACAGGGAACGCCTGAGGCCCCAGAATTCCTCATTCATCCTACTGTGTGGCTCACCACGATGAGCTT CGCAGTGTTCCTGATTCACACCGAGAGGAAAAAGGGAGTCCAGTCATCTGGAGTGCTGTTTGGTTACTGG CTTCTCTGCTTTGTCTTGCCAGCTACCAACGCTGCCCAGCAGGCCTCCGGAGCGGGCTTCCAGAGCGACC CTGTCCGCCACCTGTCCACCTACCTATGCCTGTCTCTGGTGGTGGCACAGTTTGTGCTGTCCTGCCTGGC GGATCAACCCCCCTTCTTCCCTGAAGACCCCCAGCAGTCTAACCCCTGTCCAGAGACTGGGGCAGCCTTC CCCTCCAAAGCCACGTTCTGGTGGGTTTCTGGCCTGGTCTGGAGGGGATACAGGAGGCCACTGAGACCAA AAGACCTCTGGTCGCTTGGGAGAGAAAACTCCTCAGAAGAACTTGTTTCCCGGCTTGAAAAGGAGTGGAT GAGGAACCGCAGTGCAGCCCGGAGGCACAACAAGGCAATAGCATTTAAAAGGAAAGGCGGCAGTGGCATG AAGGCTCCAGAGACCGAGCCCTTCCTACGGCAAGAAGGGAGCCAGTGGCGCCCACTGCTGAAGGCCATCT GGCAGGTGTTCCATTCTACCTTCCTCCTGGGGACCCTCAGCCTCATCATCAGTGATGTCTTCAGGTTCAC TGTCCCCAAGCTGCTCAGCCTTTTCCTGGAGTTTATTGGTGATCCCAAGCCTCCAGCCTGGAAGGGCTAC CTCCTCGCCGTGCTGATGTTCCTCTCAGCCTGCCTGCAAACGCTGTTTGAGCAGCAGAACATGTACAGGC TCAAGGTGCTGCAGATGAGGTTGCGGTCGGCCATCACTGGCCTGGTGTACAGAAAGGTCCTGGCTCTGTC CAGCGGCTCCAGAAAGGCCAGTGCGGTGGGTGATGTGGTCAATCTGGTGTCCGTGGACGTGCAGCGGCTG ACCGAGAGCGTCCTCTACCTCAACGGGCTGTGGCTGCCTCTCGTCTGGATCGTGGTCTGCTTCGTCTATC TCTGGCAGCTCCTGGGGCCCTCCGCCCTCACTGCCATCGCTGTCTTCCTGAGCCTCCTCCCTCTGAATTT CTTCATCTCCAAGAAAAGGAACCACCATCAGGAGGAGCAAATGAGGCAGAAGGACTCACGGGCACGGCTC ACCAGCTCTATCCTCAGGAACTCGAAGACCATCAAGTTCCATGGCTGGGAGGGAGCCTTTCTGGACAGAG TCCTGGGCATCCGAGGCCAGGAGCTGGGCGCCTTGCGGACCTCCGGCCTCCTCTTCTCTGTGTCGCTGGT GTCCTTCCAAGTGTCTACATTTCTGGTCGCACTGGTGGTGTTTGCTGTCCACACTCTGGTGGCCGAGAAT GCTATGAATGCAGAGAAAGCCTTTGTGACTCTCACAGTTCTCAACATCCTCAACAAGGCCCAGGCTTTCC TGCCCTTCTCCATCCACTCCCTCGTCCAGGCCCGGGTGTCCTTTGACCGTCTGGTCACCTTCCTCTGCCT GGAAGAAGTTGACCCTGGTGTCGTAGACTCAAGTTCCTCTGGAAGCGCTGCCGGGAAGGATTGCATCACC ATACACAGTGCCACCTTCGCCTGGTCCCAGGAAAGCCCTCCCTGCCTCCACAGAATAAACCTCACGGTGC CCCAGGGCTGTCTGCTGGCTGTTGTCGGTCCAGTGGGGGCAGGGAAGTCCTCCCTGCTGTCCGCCCTCCT TGGGGAGCTGTCAAAGGTGGAGGGGTTCGTGAGCATCGAGGGTGCTGTGGCCTACGTGCCCCAGGAGGCC TGGGTGCAGAACACCTCTGTGGTAGAGAATGTGTGCTTCGGGCAGGAGCTGGACCCACCCTGGCTGGAGA GAGTACTAGAAGCCTGTGCCCTGCAGCCAGATGTGGACAGCTTCCCTGAGGGAATCCACACTTCAATTGG GGAGCAGGGCATGAATCTCTCCGGAGGCCAGAAGCAGCGGCTGAGCCTGGCCCGGGCTGTATACAGAAAG GCAGCTGTGTACCTGCTGGATGACCCCCTGGCGGCCCTGGATGCCCACGTTGGCCAGCATGTCTTCAACC AGGTCATTGGGCCTGGTGGGCTACTCCAGGGAACAACACGGATTCTCGTGACGCACGCACTCCACATCCT GCCCCAGGCTGATTGGATCATAGTGCTGGCAAATGGGGCCATCGCAGAGATGGGTTCCTACCAGGAGCTT CTGCAGAGGAAGGGGGCCCTCGTGTGTCTTCTGGATCAAGCCAGACAGCCAGGAGATAGAGGAGAAGGAG AAACAGAACCTGGGACCAGCACCAAGGACCCCAGAGGCACCTCTGCAGGCAGGAGGCCCGAGCTTAGACG CGAGAGGTCCATCAAGTCAGTCCCTGAGAAGGACCGTACCACTTCAGAAGCCCAGACAGAGGTTCCTCTG GATGACCCTGACAGGGCAGGATGGCCAGCAGGAAAGGACAGCATCCAATACGGCAGGGTGAAGGCCACAG TGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCA GCAAGTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAG CAGACGCAGGCAGCCCTGCGTGGCGGGATCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTG CCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAGGTTGCTCTTCCAGAGGCTCCTGTGGGA TGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCTCCAAG GAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCC TGGAGGTCAGCCTGGTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCT CTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCTCATGCCAGCTGAGACGCTTGGAGTCAGCCAGCTAC TCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCGGGCATTCCGAACCCAGG CCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGC TGACAGGTGGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCT GTGCTGAGCAAAGCCCACCTCAGTGCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCC AGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACAGCATCGTGTCAGTGGAGCGGATGCA GGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCCCTGGCCT CAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGG GCGTGTCCTTCAAGATCCACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTC CCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGCAGCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATT GCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACCCCATCCTGTTCCCTG GCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGAC GGTGCAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAG GACCTGAGCGTGGGCCAGAAACAGCTCCTGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCA TCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCTGCAGATGCAGGCCATGCTCGGGAGCTG GTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGGTTCTG GTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTT ACAGACTGGCCCAGGAGTCAGGCCTGGTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211938 representing NM_001171
Red=Cloning site Green=Tags(s) MAAPAEPCAGQGVWNQTEPEPAATSLLSLCFLRTAGVWVPPMYLWVLGPIYLLFIHHHGRGYLRMSPLFK AKMVLGFALIVLCTSSVAVALWKIQQGTPEAPEFLIHPTVWLTTMSFAVFLIHTERKKGVQSSGVLFGYW LLCFVLPATNAAQQASGAGFQSDPVRHLSTYLCLSLVVAQFVLSCLADQPPFFPEDPQQSNPCPETGAAF PSKATFWWVSGLVWRGYRRPLRPKDLWSLGRENSSEELVSRLEKEWMRNRSAARRHNKAIAFKRKGGSGM KAPETEPFLRQEGSQWRPLLKAIWQVFHSTFLLGTLSLIISDVFRFTVPKLLSLFLEFIGDPKPPAWKGY LLAVLMFLSACLQTLFEQQNMYRLKVLQMRLRSAITGLVYRKVLALSSGSRKASAVGDVVNLVSVDVQRL TESVLYLNGLWLPLVWIVVCFVYLWQLLGPSALTAIAVFLSLLPLNFFISKKRNHHQEEQMRQKDSRARL TSSILRNSKTIKFHGWEGAFLDRVLGIRGQELGALRTSGLLFSVSLVSFQVSTFLVALVVFAVHTLVAEN AMNAEKAFVTLTVLNILNKAQAFLPFSIHSLVQARVSFDRLVTFLCLEEVDPGVVDSSSSGSAAGKDCIT IHSATFAWSQESPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGAVAYVPQEA WVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRK AAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQEL LQRKGALVCLLDQARQPGDRGEGETEPGTSTKDPRGTSAGRRPELRRERSIKSVPEKDRTTSEAQTEVPL DDPDRAGWPAGKDSIQYGRVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADDPAVGGQ QTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSK ETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASY SSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCA VLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPWP QGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPI AHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGE DLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVL VMDKGQVAESGSPAQLLAQKGLFYRLAQESGLV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001171 |
| ORF Size | 4509 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001171.5 |
| RefSeq Size | 4535 bp |
| RefSeq ORF | 4512 bp |
| Locus ID | 368 |
| UniProt ID | O95255 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters |
| MW | 164.7 kDa |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Premature Termination Codon Read-Through in the ABCC6 Gene: Potential Treatment for Pseudoxanthoma Elasticum
,null,
The Journal of investigative dermatology
,PubMed ID 23702584
[ABCC6]
|
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211938L1 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1, Myc-DDK-tagged |
CNY 17,824.00 |
|
| RC211938L2 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1, mGFP tagged |
CNY 16,910.00 |
|
| RC211938L3 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1, Myc-DDK-tagged |
CNY 16,910.00 |
|
| RC211938L4 | Lenti ORF clone of Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1, mGFP tagged |
CNY 17,824.00 |
|
| RG211938 | ABCC6 (tGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1 |
CNY 17,024.00 |
|
| SC309046 | ABCC6 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6), transcript variant 1 |
CNY 15,432.00 |
