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Activin Receptor Type IIA (ACVR2A) (NM_001616) Human Untagged Clone
CAT＃: SC125520
ACVR2A (untagged)-Human activin A receptor, type IIA (ACVR2A)
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACTRII; ACVR2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125520 sequence for NM_001616 edited (data generated by NextGen Sequencing)
ATGGGAGCTGCTGCAAAGTTGGCGTTTGCCGTCTTTCTTATCTCCTGTTCTTCAGGTGCT ATACTTGGTAGATCAGAAACTCAGGAGTGTCTTTTCTTTAATGCTAATTGGGAAAAAGAC AGAACCAATCAAACTGGTGTTGAACCGTGTTATGGTGACAAAGATAAACGGCGGCATTGT TTTGCTACCTGGAAGAATATTTCTGGTTCCATTGAAATAGTGAAACAAGGTTGTTGGCTG GATGATATCAACTGCTATGACAGGACTGATTGTGTAGAAAAAAAAGACAGCCCTGAAGTA TATTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAAGTTTTCTTATTTTCCAGAGATG GAAGTCACACAGCCCACTTCAAATCCAGTTACACCTAAGCCACCCTATTACAACATCCTG CTCTATTCCTTGGTGCCACTTATGTTAATTGCGGGGATTGTCATTTGTGCATTTTGGGTG TACAGGCATCACAAGATGGCCTACCCTCCTGTACTTGTTCCAACTCAAGACCCAGGACCA CCCCCACCTTCTCCATTACTAGGTTTGAAACCACTGCAGTTATTAGAAGTGAAAGCAAGG GGAAGATTTGGTTGTGTCTGGAAAGCCCAGTTGCTTAACGAATATGTGGCTGTCAAAATA TTTCCAATACAGGACAAACAGTCATGGCAAAATGAATACGAAGTCTACAGTTTGCCTGGA ATGAAGCATGAGAACATATTACAGTTCATTGGTGCAGAAAAACGAGGCACCAGTGTTGAT GTGGATCTTTGGCTGATCACAGCATTTCATGAAAAGGGTTCACTATCAGACTTTCTTAAG GCTAATGTGGTCTCTTGGAATGAACTGTGTCATATTGCAGAAACCATGGCTAGAGGATTG GCATATTTACATGAGGATATACCTGGCCTAAAAGATGGCCACAAACCTGCCATATCTCAC AGGGACATCAAAAGTAAAAATGTGCTGTTGAAAAACAACCTGACAGCTTGCATTGCTGAC TTTGGGTTGGCCTTAAAATTTGAGGCTGGCAAGTCTGCAGGCGATACCCATGGACAGGTT GGTACCCGGAGGTACATGGCTCCAGAGGTATTAGAGGGTGCTATAAACTTCCAAAGGGAT GCATTTTTGAGGATAGATATGTATGCCATGGGATTAGTCCTATGGGAACTGGCTTCTCGC TGTACTGCTGCAGATGGACCTGTAGATGAATACATGTTGCCATTTGAGGAGGAAATTGGC CAGCATCCATCTCTTGAAGACATGCAGGAAGTTGTTGTGCATAAAAAAAAGAGGCCTGTT TTAAGAGATTATTGGCAGAAACATGCTGGAATGGCAATGCTCTGTGAAACCATTGAAGAA TGTTGGGATCACGACGCAGAAGCCAGGTTATCAGCTGGATGTGTAGGTGAAAGAATTACC CAGATGCAGAGACTAACAAATATTATTACCACAGAGGACATTGTAACAGTGGTCACAATG GTGACAAATGTTGACTTTCCTCCCAAAGAATCTAGTCTATGA Clone variation with respect to NM_001616.3 354 g=>a >OriGene 5' read for NM_001616 unedited
TTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGTTTTGTTCCGAGAGACG GGAGAGGCGAGCGGAGCTGACAGTGATTTTGACAGTGATTTAAACCCGCTTTTGTTGTTG TTGGCTTTTCGTTGTTTGGTTTTGTGTGTTGTGCGTGTGTGTGGCGGTTTTTCCCCCGTG GTGCATTTTATTTTTTATCGTTGTGCTCTTTTTTTTCTTTTTTTTTTTTTTAACCCAGTG AGCGNNNNTTTTTTTTTTTTTTTTTTTTTTTTTGGGGCTGGGCTTCCGAATATGTTTTAT GACGGTTGATTTTACACCAGGAGGTTTGTCTCCGAGGAAAACCCAGGGAACTGGTTTTTT AGCGAGAACTTCCTCCGGATTCCCCGGCGCCTCGGGAAAATGGGAGCTGCTGCAAAGTTG GCGTTTGCCGTCTTTTTTATCTCCTGTTCTTCAGGGGCTATACTTGGTAAATCAAAAACT CAGGAGGGGCTTTTCTTTAATGCTAATTGGGAAAAAGACAGAACCCATCAAACTGGTGTT GAACCGTGTTATGGTGACAAAAATAAACGGCGGCTTTGTTTTGCTACCTGGAAGAATATT TCTGGTTCCATTGAAATAGGGAAACAAGGGTTGTTTGGCTGGATGATATCAACTGCTATT ACAGGACTGATTGTGTAAAAAAAAAAACAGCCCTGAAGTTATTTTTTGTTGCTGGGAGGG CATATTTGAATGAAAAAGTTTTTTATTTTCCAAATTGGAGTCCCCACCCCCTTTAATTCA GTTCACCTAACCCCCCTTACACAATCCTGTTTATTCCTTGGGCCCCTATGGTATTGGGGG GGGATTGGCTTTTGGCCTTTTGGGGGGGCCAGCTTCACAAAATGGCTACCTCCTGGCCTG TTCCACTAAGAACAGAACCCCCCCCTTCATTATTTTGGG >OriGene 3' read for NM_001616 unedited
NNNNTTTTAGCTNTGNAACCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTAAATTTCATGATATGATTCTATTTTAAATTCCAAGGGGTTGGG TTTTTTCCTGATTGTATTTTCAAAACATCACCATGAAAGATAGATAGTGCAAGTTCATGG GACTAACAATCGTGAAGCACAGTCTCTTTTTCTGGAATTCACAAGGTACCTAGAATTCAA ACAAGAATCACACATCACATGCTAAAAAAACTTCTAGCATCTAAAATACATACAAGAGCT GTGCAGGGCATAAACTTCAAATAAAGCCGAACACTGGTTAATCCATCAGTCCTATGGCAA GTTGATCATAAAGCATTCCTTACGCGGAGATCTGGGCAAGGTAAAGAGTATAAGTTAGAG CAGCAGCAGTTCTGATGGGTATCAAAAAGGCAAAATACAAGACGAGTCATGAGGAGCACC ATACACATGAGGAAAGAGTTATTTGGGGGGTCTCAGTTTGCCCCAAAATGGATCACCATT TTTCTCATTCTTTGATCTTTTTTTTTTCCAGTATCTCTAGCTCAAACTTTCTGTTAACTT GCCCACTCTGCACTGACTGTAAACCAAACACTAAATACCCTGCAAAAGAAAGTTTTAACA AGACTAGGTATAAAGACAGGTAGTCACTGGAACCATTCTATTTTACTGCTTATAAAAAGT TTTTCTATTAATAAAAAGTTCTCAAAAGATAACAGTTTTTAAATTGGTTAACCTCCGTTA AATACAATACCCCGGGATTCTAAAAAATTTTTTCTACCTGGAAAACTTTTTTATGTGGAA AAACTGGGTTTAAAAATTTATTTCTTGGCCTCCCTAACCCCAAACTTTCTATAAATTCCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001616 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001616.3, NP_001607.1 |
| RefSeq Size | 5244 bp |
| RefSeq ORF | 1542 bp |
| Locus ID | 92 |
| UniProt ID | P27037 |
| Domains | Activin_recp, pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210227 | ACVR2A (Myc-DDK-tagged)-Human activin A receptor, type IIA (ACVR2A) |
CNY 5,728.00 |
|
| RC210227L1 | Lenti ORF clone of Human activin A receptor, type IIA (ACVR2A), Myc-DDK-tagged |
CNY 8,128.00 |
|
| RC210227L2 | Lenti ORF clone of Human activin A receptor, type IIA (ACVR2A), mGFP tagged |
CNY 5,890.00 |
|
| RC210227L3 | Lenti ORF clone of Human activin A receptor, type IIA (ACVR2A), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210227L4 | Lenti ORF clone of Human activin A receptor, type IIA (ACVR2A), mGFP tagged |
CNY 8,128.00 |
|
| RG210227 | ACVR2A (tGFP-tagged) - Human activin A receptor, type IIA (ACVR2A) |
CNY 7,328.00 |
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