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MCM7 (NM_005916) Human Untagged Clone
CAT＃: SC128224
MCM7 (untagged)-Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS146; PPP1R104 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128224 sequence for NM_005916 edited (data generated by NextGen Sequencing)
ATGGCACTGAAGGACTACGCGCTAGAGAAGGAAAAGGTTAAGAAGTTCTTACAAGAGTTC TACCAGGATGATGAACTCGGGAAGAAGCAGTTCAAGTATGGGAACCAGTTGGTTCGGCTG GCTCATCGGGAACAGGTGGCTCTGTATGTGGACCTGGACGACGTAGCCGAGGATGACCCC GAGTTGGTGGACTCAATTTGTGAGAATGCCAGGCGCTACGCGAAGCTCTTTGCTGATGCC GTACAAGAGCTGCTGCCTCAGTACAAGGAGAGGGAAGTGGTAAATAAAGATGTCCTGGAC GTTTACATTGAGCATCGGCTAATGATGGAGCAGCGGAGTCGGGACCCTGGGATGGTCCGA AGCCCCCAGAACCAGTACCCTGCTGAACTCATGCGCAGATTTGAGCTGTATTTTCAAGGC CCTAGCAGCAACAAGCCTCGTGTGATCCGGGAAGTGCGGGCTGACTCTGTGGGGAAGTTG GTAACTGTGCGTGGAATCGTCACTCGTGTCTCTGAAGTCAAACCCAAGATGGTGGTGGCC ACTTACACTTGTGACCAGTGTGGGGCAGAGACCTACCAGCCGATCCAGTCTCCCACTTTC ATGCCTCTGATCATGTGCCCAAGCCAGGAGTGCCAAACCAACCGCTCAGGAGGGCGGCTG TATCTGCAGACACGGGGCTCCAGATTCATCAAATTCCAGGAGATGAAGATGCAAGAACAT AGTGATCAGGTGCCTGTGGGAAATATCCCTCGTAGTATCACGGTGCTGGTAGAAGGAGAG AACACAAGGATTGCCCAGCCTGGAGACCACGTCAGCGTCACTGGTATTTTCTTGCCAATC CTGCGCACTGGGTTCCGACAGGTGGTACAGGGTTTACTCTCAGAAACCTACCTGGAAGCC CATCGGATTGTGAAGATGAACAAGAGTGAGGATGATGAGTCTGGGGCTGGAGAGCTCACC AGGGAGGAGCTGAGGCAAATTGCAGAGGAGGATTTCTACGAAAAGCTGGCAGCTTCAATC GCCCCAGAAATATACGGGCATGAAGATGTGAAGAAGGCACTGCTGCTCCTGCTAGTCGGG GGTGTGGACCAGTCTCCTCGAGGCATGAAAATCCGGGGCAACATCAACATCTGTCTGATG GGGGATCCTGGTGTGGCCAAGTCTCAGCTCCTGTCATACATTGATCGACTGGCGCCTCGC AGCCAGTACACAACAGGCCGGGGCTCCTCAGGAGTGGGGCTTACGGCAGCTGTGCTGAGA GACTCCGTGAGTGGAGAACTGACCTTAGAGGGTGGGGCCCTGGTGCTGGCTGACCAGGGT GTGTGCTGCATTGATGAGTTCGACAAGATGGCTGAGGCCGACCGCACAGCCATCCACGAG GTCATGGAGCAGCAGACCATCTCCATTGCCAAGGCCGGCATTCTCACCACACTCAATGCC CGCTGCTCCATCCTGGCTGCCGCCAACCCTGCCTACGGGCGCTACAACCCTCGCCGCAGC CTGGAGCAGAACATACAGCTACCTGCTGCACTGCTCTCCCGGTTTGACCTCCTCTGGCTG ATTCAGGACCGGCCCGACCGAGACAATGACCTACGGTTGGCCCAGCACATTACCTATGTG CACCAGCACAGCCGGCAGCCCCCCTCCCAGTTTGAACCTCTGGACATGAAGCTCATGAGG CGTTACATAGCCATGTGCCGCGAGAAGCAGCCCATGGTGCCAGAGTCTCTGGCTGACTAC ATCACAGCAGCATACGTGGAGATGAGGCGAGAGGCTTGGGCTAGTAAGGATGCCACCTAT ACTTCTGCCCGGACCCTGCTGGCTATCCTGCGCCTTTCCACTGCTCTGGCACGTCTGAGA ATGGTGGATGTGGTGGAGAAAGAAGATGTGAATGAAGCCATCAGGCTAATGGAGATGTCA AAGGACTCTCTTCTAGGAGACAAGGGGCAGACAGCTAGGACTCAGAGACCAGCAGATGTG ATATTTGCCACCGTCCGTGAACTGGTCTCAGGGGGCCGAAGTGTCCGGTTCTCTGAGGCA GAGCAGCGCTGTGTATCTCGTGGCTTCACACCCGCCCAGTTCCAGGCGGCTCTGGATGAA TATGAGGAGCTCAATGTCTGGCAGGTCAATGCTTCCCGGACACGGATCACTTTTGTCTGA Clone variation with respect to NM_005916.3 1611 c=>t >OriGene 5' read for NM_005916 unedited
TCAGTATATTTGTATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGTGCGCTG GCCCTTTAAGAGCGATTCTCCTCCGCCCGCGCCAGCTCGGACCGCGGGAAACCCGGCGCC TGCACTACCCCGCCCGGAGATTCCCTTCCGACGCCCGCACCGCCTCCCCGTCACTCATTC TAGGCCCGCACGGTGATTGGCTTGCGGCTAGCGGGAGGTGAAGAAGGCCGCCTTGTCCGA TTGGCCCGCACGCAGTGGCGCCGGTCACGTGGGGGGCGACGTTTCGCGCCAATTTCGGTT GGCCGGCCACAGTCCACCGCGCGGAGATTCTCAGCTTCCCCAGGAGCAAGACCTCTGAGC CCGCCAAGCGCGGCCGCACGGCCCTCGGCAGCGATGGCACTGAAGGACTACGCGCTAGAG AAGGAAAAGGTTAAGAAGTTCTTACAAGAGTTCTACCAGGATGATGAACTCGGGAAGAAG CAGTTCAAGTATGGGAACCAGTTGGTTCGGCTGGCTCATCGGGAACAGGTGGCTCTGTAT GTGGACCTGGACGACGTANCCCGAGATGACCCCGAGTTGGTGGACTCAATTTGTGAGAAT GCCAGGCGCTACGCGAAGCTCTTTGCTGATGCCGTACAAGAGCTGCTGCCTCAGTCCAGG AGAGGGAAGTGTAAATAAAGATGCCTGGACGTTACATTGAGCATCGGCTATGATGGACAN NCGAGTCCAACCCTGGGATGGTCCGAGCCCCCAAACCAGTACCCTGCTGAACTCTGCGCA GATTGAGCTGTATTTTCAAGGCCTAACAGCACAGCCTCGTGTGATCCGGGAGTGCGGCTG ACTTGGGGGGAAGTGGTACTGTGCGTGAATCGNACTCGTGCTCTGAGTCAACCCAGATGG GGTGGCACCTAACTGGGACCGTGTGGGCAAAACTACAGCGATCAGNTCCCTTTATGCTTT GAATGGGCAGNCAGATGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005916 |
| Insert Size | 2650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005916.3, NP_005907.3 |
| RefSeq Size | 2821 bp |
| RefSeq ORF | 2160 bp |
| Locus ID | 4176 |
| UniProt ID | P33993 |
| Domains | MCM, AAA |
| Protein Families | Transcription Factors |
| Protein Pathways | Cell cycle, DNA replication |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The miR-106b∼25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300
,Zhou, Y;Hu, Y;Yang, M;Jat, P;Li, K;Lombardo, Y;Xiong, D;Coombes, RC;Raguz, S;Yagüe, E;,
Cell Death Differ.
,PubMed ID 24270410
[MCM7]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213809 | MCM7 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1 |
CNY 3,990.00 |
|
| RC213809L1 | Lenti ORF clone of Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213809L2 | Lenti ORF clone of Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC213809L3 | Lenti ORF clone of Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213809L4 | Lenti ORF clone of Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG213809 | MCM7 (tGFP-tagged) - Human minichromosome maintenance complex component 7 (MCM7), transcript variant 1 |
CNY 4,370.00 |
