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GAMT (NM_000156) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC200528L1V
- LentiORF®
-
Lenti ORF particles, GAMT (Myc-DDK-tagged)-Human guanidinoacetate N-methyltransferase (GAMT), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,410.00
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| Product Data | |
| Product Name | GAMT (NM_000156) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CCDS2; HEL-S-20; PIG2; TP53I2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_000156 |
| ORF Size | 708 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC200528).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000156.5 |
| RefSeq Size | 1138 bp |
| RefSeq ORF | 711 bp |
| Locus ID | 2593 |
| Protein Families | Druggable Genome |
| Protein Pathways | Arginine and proline metabolism, Glycine, serine and threonine metabolism, Metabolic pathways |
| MW | 26.3 kDa |
| Gene Summary | The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012] |
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