United States
Germany
Japan
United Kingdom
China
Axin 1 (AXIN1) (NM_181050) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208349L1V
- LentiORF®
-
Lenti ORF particles, AXIN1 (Myc-DDK tagged) - Human axin 1 (AXIN1), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Axin 1 (AXIN1) (NM_181050) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AXIN; PPP1R49 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_181050 |
| ORF Size | 2478 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208349).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_181050.1 |
| RefSeq Size | 3369 bp |
| RefSeq ORF | 2481 bp |
| Locus ID | 8312 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - Wnt Signaling pathway |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Wnt signaling pathway |
| MW | 91.5 kDa |
| Gene Summary | This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
