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Complement C3 (C3) (NM_000064) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC215069L3V
- LentiORF®
-
Lenti ORF particles, C3 (Myc-DDK-tagged)-Human complement component 3 (C3), 200ul, >10^7 TU/mL
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CNY 11,210.00
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规格
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Specifications
| Product Data | |
| Product Name | Complement C3 (C3) (NM_000064) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_000064 |
| ORF Size | 4989 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215069).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000064.1, NP_000055.1 |
| RefSeq Size | 5067 bp |
| RefSeq ORF | 4992 bp |
| Locus ID | 718 |
| Domains | ANATO, NTR, A2M, A2M_N |
| Protein Families | Druggable Genome |
| Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
| MW | 187 kDa |
| Gene Summary | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015] |
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