Prohibitin (PHB) Human Gene Knockout Kit (CRISPR)

CAT#: KN201229BN

PHB - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal Anti-PHB Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


PHB (Myc-DDK-tagged)-Human prohibitin (PHB)
    • 10 ug

CNY 2,400.00
CNY 4,465.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Prohibitin
Locus ID 5245
Kit Components

KN201229G1, Prohibitin gRNA vector 1 in pCas-Guide CRISPR vector

KN201229G2, Prohibitin gRNA vector 2 in pCas-Guide CRISPR vector

KN201229BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001281496, NM_001281497, NM_001281715, NM_002634
Synonyms HEL-215; HEL-S-54e; PHB1
Summary This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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