EIF4A2 Human Gene Knockout Kit (CRISPR)

CAT#: KN205623RB

EIF4A2 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


EIF4A2 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


EIF4A2 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 4A2 (EIF4A2)
    • 10 ug

CNY 3,656.00
CNY 3,990.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol EIF4A2
Locus ID 1974
Kit Components

KN205623G1, EIF4A2 gRNA vector 1 in pCas-Guide CRISPR vector

KN205623G2, EIF4A2 gRNA vector 2 in pCas-Guide CRISPR vector

KN205623RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001967
Synonyms BM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F
Summary ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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