USP7 Human Gene Knockout Kit (CRISPR)

CAT#: KN213986RB

USP7 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


USP7 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


USP7 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 7 (herpes virus-associated) (USP7)
    • 10 ug

CNY 11,512.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol USP7
Locus ID 7874
Kit Components

KN213986G1, USP7 gRNA vector 1 in pCas-Guide CRISPR vector

KN213986G2, USP7 gRNA vector 2 in pCas-Guide CRISPR vector

KN213986RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001286457, NM_001286458, NM_003470, NM_001321858, NR_135826
Synonyms HAUSP; TEF1
Summary The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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