Cortactin (CTTN) (NM_138565) Human Mass Spec Standard

CAT#: PH301111

CTTN MS Standard C13 and N15-labeled recombinant protein (NP_612632)



  View other "Cortactin" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of cortactin (CTTN), transcript variant 2
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CTTN Antibody - N-terminal region
    • 50 ug

CNY 4,628.00

Specifications

Product Data
Description CTTN MS Standard C13 and N15-labeled recombinant protein (NP_612632)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201111
Predicted MW 57.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_612632
RefSeq Size 3208
RefSeq ORF 1539
Synonyms EMS1
Locus ID 2017
Cytogenetics 11q13.3
Summary This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Protein Families Druggable Genome
Protein Pathways Pathogenic Escherichia coli infection, Tight junction
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