PLAUR (NM_002659) Human Mass Spec Standard

CAT#: PH301222

PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_002650)



  View other "PLAUR" proteins (10)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 2
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Specifications

Product Data
Description PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_002650)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201222
Predicted MW 37 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002650
RefSeq Size 1570
RefSeq ORF 1005
Synonyms CD87; U-PAR; UPAR; URKR
Locus ID 5329
Cytogenetics 19q13.31
Summary This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades
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