Selenophosphate synthetase 2 (SEPHS2) (NM_012248) Human Mass Spec Standard

CAT#: PH301830

SEPHS2 MS Standard C13 and N15-labeled recombinant protein (NP_036380)



  View other "Selenophosphate synthetase 2" proteins (3)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of selenophosphate synthetase 2 (SEPHS2)
    • 100 ug

CNY 3,080.00


Rabbit polyclonal antibody to SEPHS2 (selenophosphate synthetase 2)
    • 100 ul

CNY 6,281.00

Specifications

Product Data
Description SEPHS2 MS Standard C13 and N15-labeled recombinant protein (NP_036380)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201830
Predicted MW 47.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036380
RefSeq Size 2351
RefSeq ORF 1344
Synonyms SPS2
Locus ID 22928
Cytogenetics 16p11.2
Summary This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]
Protein Pathways Metabolic pathways, Selenoamino acid metabolism
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