G gamma12 (GNG12) (NM_018841) Human Mass Spec Standard

Specifications

Product Data
Description	GNG12 MS Standard C13 and N15-labeled recombinant protein (NP_061329)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203268
Predicted MW	7.9 kDa
Protein Sequence	Sequence Link (showhide) >RC203268 protein sequence Red=Cloning site Green=Tags(s) MSSKTASTNNIAQARRTVQQLRLEASIEGIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCI IL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_061329
RefSeq Size	4427
RefSeq ORF	216
Locus ID	55970
Cytogenetics	1p31.3
Summary	Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome
Protein Pathways	Chemokine signaling pathway, MAPK signaling pathway, Regulation of actin cytoskeleton

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