GJB3 (NM_001005752) Human Mass Spec Standard

Specifications

Product Data
Description	GJB3 MS Standard C13 and N15-labeled recombinant protein (NP_001005752)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204405
Predicted MW	30.8 kDa
Protein Sequence	Sequence Link (showhide) >RC204405 protein sequence Red=Cloning site Green=Tags(s) MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFP ISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLI IEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI CHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001005752
RefSeq Size	1777
RefSeq ORF	810
Synonyms	CX31; DFNA2; DFNA2B; EKV; EKVP1
Locus ID	2707
Cytogenetics	1p34.3
Summary	This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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