Osteopontin (SPP1) (NM_001040058) Human Mass Spec Standard

CAT#: PH304803

SPP1 MS Standard C13 and N15-labeled recombinant protein (NP_001035147)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description SPP1 MS Standard C13 and N15-labeled recombinant protein (NP_001035147)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204803
Predicted MW 35.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001035147
RefSeq Size 1641
RefSeq ORF 942
Synonyms BNSP; BSPI; ETA-1; OPN
Locus ID 6696
Cytogenetics 4q22.1
Summary The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway
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