Ribonuclease A (RNASE1) (NM_198235) Human Mass Spec Standard

CAT#: PH305620

RNASE1 MS Standard C13 and N15-labeled recombinant protein (NP_937878)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RNASE1 MS Standard C13 and N15-labeled recombinant protein (NP_937878)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205620
Predicted MW 17.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_937878
RefSeq Size 903
RefSeq ORF 468
Synonyms RAC1; RIB1; RNS1
Locus ID 6035
Cytogenetics 14q11.2
Summary This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Protein Families Secreted Protein, Transmembrane
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