beta 2 Microglobulin (B2M) (NM_004048) Human Mass Spec Standard

Specifications

Product Data
Description	B2M MS Standard C13 and N15-labeled recombinant protein (NP_004039)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207587
Predicted MW	13.71 kDa
Protein Sequence	Sequence Link (showhide) >RC207587 representing NM_004048 Red=Cloning site Green=Tags(s) MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVE HSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004039
RefSeq Size	987
RefSeq ORF	357
Synonyms	IMD43
Locus ID	567
Cytogenetics	15q21.1
Summary	This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Antigen processing and presentation

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