Growth Hormone (GH1) (NM_022559) Human Mass Spec Standard

CAT#: PH309608

GH1 MS Standard C13 and N15-labeled recombinant protein (NP_072053)



  View other "Growth Hormone" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of growth hormone 1 (GH1), transcript variant 1
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Specifications

Product Data
Description GH1 MS Standard C13 and N15-labeled recombinant protein (NP_072053)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209608
Predicted MW 23 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_072053
RefSeq Size 815
RefSeq ORF 606
Synonyms GH; GH-N; GHB5; GHN; hGH-N; IGHD1A; IGHD1B; IGHD2
Locus ID 2688
Cytogenetics 17q23.3
Summary The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
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