EP4 (PTGER4) (NM_000958) Human Mass Spec Standard

CAT#: PH310932

PTGER4 MS Standard C13 and N15-labeled recombinant protein (NP_000949)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Anti-PTGER4 Rabbit Polyclonal Antibody
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Specifications

Product Data
Description PTGER4 MS Standard C13 and N15-labeled recombinant protein (NP_000949)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210932
Predicted MW 53.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000949
RefSeq Size 3432
RefSeq ORF 1464
Synonyms EP4; EP4R
Locus ID 5734
Cytogenetics 5p13.1
Summary The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
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