Cytochrome p450 2C19 (CYP2C19) (NM_000769) Human Mass Spec Standard

CAT#: PH311377

CYP2C19 MS Standard C13 and N15-labeled recombinant protein (NP_000760)



  View other "Cytochrome p450 2C19" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
    • 100 ug

CNY 4,840.00


Rabbit Polyclonal Anti-CYP2C19 Antibody
    • 50 ug

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Specifications

Product Data
Description CYP2C19 MS Standard C13 and N15-labeled recombinant protein (NP_000760)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211377
Predicted MW 55.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000760
RefSeq Size 1473
RefSeq ORF 1470
Synonyms CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19
Locus ID 1557
Cytogenetics 10q23.33
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism
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