cIAP2 (BIRC3) (NM_182962) Human Mass Spec Standard

CAT#: PH311599

BIRC3 MS Standard C13 and N15-labeled recombinant protein (NP_892007)



  View other "cIAP2" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description BIRC3 MS Standard C13 and N15-labeled recombinant protein (NP_892007)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211599
Predicted MW 68.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_892007
RefSeq Size 4372
RefSeq ORF 1812
Synonyms AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49
Locus ID 330
Cytogenetics 11q22.2
Summary This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
Protein Families Druggable Genome
Protein Pathways Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
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