Cardiac Troponin T (TNNT2) (NM_001001430) Human Mass Spec Standard

CAT#: PH314241

TNNT2 MS Standard C13 and N15-labeled recombinant protein (NP_001001430)



  View other "Cardiac Troponin T" proteins (16)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description TNNT2 MS Standard C13 and N15-labeled recombinant protein (NP_001001430)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214241
Predicted MW 34.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001001430
RefSeq Size 1132
RefSeq ORF 864
Synonyms CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Locus ID 7139
Cytogenetics 1q32.1
Summary The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
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