NALP1 (NLRP1) (NM_033004) Human Mass Spec Standard

CAT#: PH316481

NLRP1 MS Standard C13 and N15-labeled recombinant protein (NP_127497)



  View other "NALP1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NLRP1 MS Standard C13 and N15-labeled recombinant protein (NP_127497)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216481
Predicted MW 165.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_127497
RefSeq Size 5617
RefSeq ORF 4419
Synonyms AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; JRRP; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1
Locus ID 22861
Cytogenetics 17p13.2
Summary This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
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