CD30 (TNFRSF8) (NM_001243) Human Mass Spec Standard

CAT#: PH319819

TNFRSF8 MS Standard C13 and N15-labeled recombinant protein (NP_001234)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description TNFRSF8 MS Standard C13 and N15-labeled recombinant protein (NP_001234)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219819
Predicted MW 63.75 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001234
RefSeq Size 3686
RefSeq ORF 1785
Synonyms CD30; D1S166E; Ki-1
Locus ID 943
Cytogenetics 1p36.22
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
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