CD11b (ITGAM) (NM_000632) Human Mass Spec Standard

CAT#: PH321743

ITGAM MS Standard C13 and N15-labeled recombinant protein (NP_000623)



  View other "CD11b" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Cited in 1 publication.

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经常一起买 (2)
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Specifications

Product Data
Description ITGAM MS Standard C13 and N15-labeled recombinant protein (NP_000623)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221743
Predicted MW 127.18 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000623
RefSeq Size 4740
RefSeq ORF 3456
Synonyms CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Locus ID 3684
Cytogenetics 16p11.2
Summary This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Leukocyte transendothelial migration, Regulation of actin cytoskeleton
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Citations (1)

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