Desmocollin 2 (DSC2) (NM_004949) Human Mass Spec Standard

CAT#: PH322207

DSC2 MS Standard C13 and N15-labeled recombinant protein (NP_004940)



  View other "Desmocollin 2" proteins (5)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of desmocollin 2 (DSC2), transcript variant Dsc2b
    • 100 ug

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Rabbit Polyclonal Anti-DSC2 Antibody
    • 100 ul

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Specifications

Product Data
Description DSC2 MS Standard C13 and N15-labeled recombinant protein (NP_004940)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222207
Predicted MW 93.77 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004940
RefSeq Size 5186
RefSeq ORF 2541
Synonyms ARVD11; CDHF2; DG2; DGII/III; DSC3
Locus ID 1824
Cytogenetics 18q12.1
Summary This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Protein Families Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)
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