Dystrobrevin alpha (DTNA) (NM_032979) Human Mass Spec Standard

CAT#: PH323952

DTNA MS Standard C13 and N15-labeled recombinant protein (NP_116761)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DTNA MS Standard C13 and N15-labeled recombinant protein (NP_116761)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223952
Predicted MW 58.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_116761
RefSeq Size 3110
RefSeq ORF 1539
Synonyms D18S892E; DRP3; DTN; DTN-A; LVNC1
Locus ID 1837
Cytogenetics 18q12.1
Summary The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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