PD L2 (PDCD1LG2) (NM_025239) Human Mass Spec Standard

Specifications

Product Data
Description	PDCD1LG2 MS Standard C13 and N15-labeled recombinant protein (NP_079515)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224141
Predicted MW	30.8 kDa
Protein Sequence	Sequence Link (showhide) >RC224141 representing NM_025239 Red=Cloning site Green=Tags(s) MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHR ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVE LTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQ SQMEPRTHPTWLLHIFIPSCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079515
RefSeq Size	1518
RefSeq ORF	819
Synonyms	B7DC; bA574F11.2; Btdc; CD273; PD-L2; PDCD1L2; PDL2
Locus ID	80380
Cytogenetics	9p24.1
Summary	Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs)

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