MASPIN (SERPINB5) (NM_002639) Human Mass Spec Standard

Specifications

Product Data
Description	SERPINB5 MS Standard C13 and N15-labeled recombinant protein (NP_002630)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224287
Predicted MW	41.9 kDa
Protein Sequence	Sequence Link (showhide) >RC224287 representing NM_002639 Red=Cloning site Green=Tags(s) MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGF QTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLT DGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFPESETKECPFRVNKTDTKPVQMMNMEATFCMGNID SINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEK MIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVVHKVCLEITEDGGDSIEVPGARILQHKDELNA DHPFIYIIRHNKTRNIIFFGKFCSP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002630
RefSeq Size	2558
RefSeq ORF	1125
Synonyms	maspin; PI5
Locus ID	5268
Cytogenetics	18q21.33
Summary	Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	p53 signaling pathway

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