Complement C3b Human Protein

Specifications

Product Data
Description	Complement C3b human protein, 0.1 mg
Species	Human
Protein Source	Serum
Concentration	lot specific
Purity	>90% by SDS-PAGE
Buffer	Presentation State: Purified State: Liquid purified Antigen Buffer System: PBS, pH 7.2 Preservative: None Stabilizer: None
Preparation	Liquid purified Antigen
Applications	ELISA.
Protein Description	Purified complemet component 3b (C3b) from Human serum.  Disease status: Source serum was tested negative for HBsAg and for antibodies to HIV and HCV.
Storage	Store (aliquotted) at -20°C. Avoid repeated freezing and thawing.
Stability	Shelf life: One year from despatch.
Reference Data
RefSeq	NP_000055
Locus ID	718
Cytogenetics	19p13.3
Synonyms	AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
Summary	Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades, Systemic lupus erythematosus

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.