GABARAPL1 (1-117, His-tag) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MGSSHHHHHH SSGLVPRGSH MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK
Tag	His-tag
Predicted MW	16.2 kDa
Concentration	lot specific
Purity	>85%
Buffer	Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris buffer (pH 8.0) containing 10% glycerol, 1 mM DTT, 0.1M NaCl
Preparation	Liquid purified protein
Protein Description	Recombinant human GABARAPL1 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_113600
Locus ID	23710
UniProt ID	Q9H0R8, A0A024RAP5
Cytogenetics	12p13.2
Synonyms	APG8-LIKE; APG8L; ATG8; ATG8B; ATG8L; GEC1
Summary	Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.[UniProtKB/Swiss-Prot Function]
Protein Pathways	Regulation of autophagy

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