FGF basic / FGF2 Mouse Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGSKGPG QKAILFLPMS AKS Result by N-terminal sequencing: ALPEDGGAAF
Predicted MW	16.34 kDa
Purity	>95%
Buffer	Presentation State: Purified State: Lyophilized freeze dried protein without additives. Buffer System: PBS without stabilizers
Preparation	Lyophilized freeze dried protein without additives.
Protein Description	Recombinant Mouse Fibroblast Growth Factor-2.
Storage	The lyophilized Mouse FGF-2, though stable at room temperature, is best stored in working aliquots at –20°C to –70°C. Avoid repeated freeze-thaw cycles
Bioactivity	Biological: The activity was determined by the stimulation of HUVE cells. The ED50 for this effect is ≤ 0.1ng/ml corresponding to a specific activity of ≥ 1 x 10e7 units/mg.
Endotoxin	< 0.1ng per μg of Mouse FGF-2
Reference Data
RefSeq	NP_032032
Locus ID	14173
UniProt ID	P15655, Q541T2
Cytogenetics	3 18.41 cM
Synonyms	bFGF; Fgf-2; Fgfb
Summary	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]

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