GAGA (1-130) Drosophila Protein

Specifications

Product Data
Species	Drosophila
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MSLPMNSLYS LTWGDYGTSL VSAIQLLRCH GDLVDCTLAA GGRSFPAHKI VLCAASPFLL DLLKNTPCKH PVVMLAGVNA NDLEALLEFV YRGEVSVDHA QLPSLLQAAQ CLNIQGLAPQ TVTKDDYTTH
Predicted MW	14 kDa
Concentration	lot specific
Purity	>95% pure by SDS-PAGE
Buffer	Presentation State: Purified State: Liquid protein Buffer System: 10 mM HEPES (pH 7.4), 25 mM NaCl
Preparation	Liquid protein
Protein Description	GAGA-POZ domain was overexpressed in E.coli and purified by using conventional chromatography techniques.
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_001034013
Summary	The GAGA factor is a sequence-specific DNA-binding protein, which participates in the regulation of the expression of a variety of different classes of genes in Drosophila such as many developmentally regulated genes, stress induced genes, and cell cycle regulated genes, as well as housekeeping genes. GAGA contains a C-terminal glutamine-rich domain and a highly conserved N-terminal POZ domain which reported to be involved in self-oligomerization in a number of other POZ domain containing proteins. In case of GAGA protein, the N-terminal POZ domain mediates the formation of oligomers both in vitro and in vivo.

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