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DRP1 (DNM1L) (NM_012062) Human Recombinant Protein
CAT＃: TP321708
Recombinant protein of human dynamin 1-like (DNM1L), transcript variant 1, 20 µg
View other "DRP1" proteins (10)
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CNY 2,900.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC221708 representing NM_012062
Red=Cloning site Green=Tags(s) MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHV SQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVV NLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRT LAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRN GTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEG TAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQ IKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIE LAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLI QDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPV PVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL TESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 81.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Bioactivity | Cell treatment (PMID: 25853493) |
| Reference Data | |
| RefSeq | NP_036192 |
| Locus ID | 10059 |
| UniProt ID | O00429, B4DYR6 |
| Refseq Size | 3293 |
| Cytogenetics | 12p11.21 |
| Refseq ORF | 2208 |
| Synonyms | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 |
| Summary | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Protective Role of PGC-1a in Diabetic Nephropathy Is Associated with the Inhibition of ROS through Mitochondrial Dynamic Remodeling
,Guo, K;Lu, J;Huang, Y;Wu, M;Zhang, L;Yu, H;Zhang, M;Bao, Y;He, JC;Chen, H;Jia, W;,
PLoS ONE
,PubMed ID 25853493
[DNM1L]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC402138 | DNM1L HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC416000 | DNM1L HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC417132 | DNM1L HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LY402138 | Transient overexpression lysate of dynamin 1-like (DNM1L), transcript variant 1 |
CNY 4,840.00 |
|
| LY416000 | Transient overexpression lysate of dynamin 1-like (DNM1L), transcript variant 2 |
CNY 3,080.00 |
|
| LY417132 | Transient overexpression lysate of dynamin 1-like (DNM1L), transcript variant 3 |
CNY 4,840.00 |
|
| PH302046 | DNM1L MS Standard C13 and N15-labeled recombinant protein (NP_036193) |
CNY 19,520.00 |
|
| PH321708 | DNM1L MS Standard C13 and N15-labeled recombinant protein (NP_036192) |
CNY 19,520.00 |
|
| TP302046 | Recombinant protein of human dynamin 1-like (DNM1L), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP701251 | Purified recombinant protein of Human dynamin 1-like (DNM1L), transcript variant 2, mutant（S590D）, 20ug |
CNY 2,900.00 |
