CD137 (TNFRSF9) (NM_001561) Human Recombinant Protein

CAT#: TP700283

Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9), with C-terminal DDK/His tag, expressed in human cells, 20 µg



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Avi-tag Biotinylated Protein
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CNY 6,650.00


货期*
4周

规格
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC200664, encoding the region (Leu24 – Leu255) of human TNFRSF9
Tag C-DDK/His
Predicted MW 20 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001552
Locus ID 3604
UniProt ID Q07011
Refseq Size 1935
Cytogenetics 1p36.23
Refseq ORF 765
Synonyms 4-1BB; CD137; CDw137; ILA
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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