CMA1 (NM_001836) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A DNA sequence from TrueORF clone, RC214873, encoding the region Gly24-Asn247 of CMA1
Tag	N-His
Predicted MW	25.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer	PBS, pH 7.4, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001827
Locus ID	1215
UniProt ID	P23946, Q4FEB3
Refseq Size	744
Cytogenetics	14q12
Refseq ORF	741
Synonyms	chymase; CYH; MCT1
Summary	This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Renin-angiotensin system

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