NEDD8 (NM_006156) Human Recombinant Protein
CAT#: TP720985XL
Purified recombinant protein of Human neural precursor cell expressed, developmentally down-regulated 8 (NEDD8)
Need it in bulk or customized? Get a free quote |
CNY 21,850.00
货期*
2周
规格
Product images
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gly76
|
Tag | N-His&SUMO |
Predicted MW | 20.9 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_006147 |
Locus ID | 4738 |
UniProt ID | Q15843 |
Refseq Size | 625 |
Cytogenetics | 14q12 |
Refseq ORF | 243 |
Synonyms | NEDD-8 |
Summary | Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.[UniProtKB/Swiss-Prot Function] |
Protein Families | Druggable Genome |
Documents
FAQs |
SDS |
Customer
Reviews
Loading...