ICOS (NM_012092) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu21-Phe141
Tag	C-Fc
Predicted MW	40.8 kDa
Concentration	lot specific
Purity	>95% as determined by SDS-PAGE and Coomassie blue staining
Buffer	Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
Storage	Store at -80°C.
Stability	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin	Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq	NP_036224
Locus ID	29851
UniProt ID	Q9Y6W8, Q53QY6
Refseq Size	2652
Cytogenetics	2q33.2
Refseq ORF	597
Synonyms	AILIM; CD278; CVID1
Summary	The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway

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