IL17F (NM_052872) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Human IL-17F, the region of Arg31-Gln163, from gene Accession# NM_052872
Tag	Tag Free
Predicted MW	14.9 kDa
Concentration	lot specific
Purity	>98%, as determined by Coomassie stained SDS-PAGE.
Buffer	1 x PBS
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	The ED50 is 400 - 800 ng/ml, corresponding to a specific activity of 2.5 ??1.25 x 10^3 units/mg, determined by the dose dependent stimulation of CXCL1 production in human fibroblast.
Endotoxin	Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_443104
Locus ID	112744
UniProt ID	Q96PD4, Q6NSI0
Refseq Size	808
Cytogenetics	6p12.2
Refseq ORF	489
Synonyms	CANDF6; IL-17F; ML-1; ML1
Summary	The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Secreted Protein

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