IL13 (NM_002188) Human Recombinant Protein

CAT#: TP723715

Purified recombinant protein of Human interleukin 13 (IL13)



  View other "IL13" proteins (3)

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CNY 5,330.00


货期*
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规格
    • 10 ug

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经常一起买 (1)
IL13 mouse monoclonal antibody, clone OTI6D3 (formerly 6D3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Human IL-13, the region of Gly21-Asn132, from gene Accession# NM_002188
Tag Tag Free
Predicted MW 12 kDa
Concentration lot specific
Purity Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity The ED50 is 1.5 to 3ng/ml, corresponding to a specific activity of 6.6 -- 3.3 x 10^5units/mg, determined by the dose dependent stimulation of TF-1 cells proliferation.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq NP_002179
Locus ID 3596
UniProt ID P35225
Refseq Size 1282
Cytogenetics 5q31.1
Refseq ORF 438
Synonyms IL-13; P600
Summary This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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