FGF2 (NM_002006) Human Recombinant Protein

CAT#: TP723719

Purified recombinant protein of Human fibroblast growth factor 2 (basic) (FGF2)



  View other "FGF2" proteins (5)

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CNY 3,030.00


货期*
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规格
    • 10 ug

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经常一起买 (1)
bFGF (FGF2) mouse monoclonal antibody, clone OTI3D9 (formerly 3D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Human FGF-basic, the region of Ala144-Ser288, from gene Accession# NM_002006
Tag Tag Free
Predicted MW 16.3 kDa
Concentration lot specific
Purity Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 10 mM NaH2PO4, 150 mM NaCl, pH 7.2, 1 mM DTT
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity The ED50 is 1 - 4 ng/ml, corresponding to a specific activity of 1 - 0.25 x 10^6 units/mg, determined by the dose dependent stimulation of NIH/ 3T3 cell proliferation. The bioactivity is equivalent to competitor reported values.
Endotoxin Less than 0.01 ng per ug protein as determined by the LAL method
Reference Data
RefSeq NP_001997
Locus ID 2247
UniProt ID P09038
Refseq Size 6803
Cytogenetics 4q28.1
Refseq ORF 864
Synonyms BFGF; FGF-2; FGFB; HBGF-2
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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