NGAL (LCN2) (NM_005564) Human Recombinant Protein

CAT#: TP723847

Purified recombinant protein of Human lipocalin 2 (LCN2 / NGAL)



  View other "NGAL" proteins (7)

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CNY 4,090.00


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规格
    • 10 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Human NGAL, the region of Gln21-Gly198, from gene Accession# NP_005555
Tag C-His
Predicted MW 22 kDa
Concentration lot specific
Purity >95%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity The BC50 = 1.2 µM, determined by dose dependent binding of the protein (4 µM) with [ Fe3+(DHBA)3] complex.
Endotoxin Less than 0.01 ng per µg protein as determine by the LAL method
Reference Data
RefSeq NP_005555
Locus ID 3934
UniProt ID P80188
Refseq Size 840
Cytogenetics 9q34.11
Refseq ORF 594
Synonyms 24p3; MSFI; NGAL; p25
Summary This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Protein Families Secreted Protein
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