CEACAM1 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gln35-Gly428
Tag	C-His
Buffer	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Note	Recombinant Human CEACAM1 (C-His) is produced by Human Cells. The target gene encoding Gln35-Gly428 is expressed with a C-His tag.
Stability	12 months from date of despatch
Reference Data
Locus ID	634
UniProt ID	P13688
Summary	Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.

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