Ifng Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Expi293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) His23-Cys155
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note	Recombinant Mouse Interferon Gamma is produced by our Mammalian expression system and the target gene encoding His23-Cys155 is expressed.
Stability	12 months from date of despatch
Reference Data
Locus ID	15978
UniProt ID	P01580
Summary	Mouse Interferon-gamma (IFN-γ/IFNG) is a secreted protein that belongs to the type II (gamma) interferon family. IFNG is primarily expressed by T lymphocytes, and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells as well as enhance the antitumor effects of the type I interferons. IFNG also functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis.

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