Cynomolgus Recombinant Protein
CAT#: TP726995
Recombinant Cynomolgus CD27 molecule/CD27(C-6His)
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CNY 3,420.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Cynomolgus |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Thr21-Ile192
|
Tag | C-His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. |
Note | Recombinant Cynomolgus CD27 molecule is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a 6His tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Summary | CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7 ,belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity. |
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