CD64 (FCGR1A) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gln16-Pro288
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Note	Recombinant Human High affinity immunoglobulin gamma Fc receptor I is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	2209
UniProt ID	P12314
Summary	CD64 (FcγRI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors FcγRII and FcγRIII. It is normally expressed on the surfaces of monocytes and macrophages.

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