IL33 Rhesus Recombinant Protein

Specifications

Product Data
Species	Rhesus
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ser112-Ile270
Tag	N-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
Note	Recombinant Rhesus macaque Interleukin 33 is produced by our E.coli expression system and the target gene encoding Ser112-Ile270 is expressed with a 6His tag at the N-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	717301
Summary	Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

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