Entpd2 Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Cys26-Ser462
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of 50mM Tris-HCl, 10mM CaCl2, 150mM NaCl, 10% Glycerol, pH 7.5 .
Note	Recombinant Mouse Ecto-Nucleoside Triphosphate Diphosphohydrolase 2 is produced by our Mammalian expression system and the target gene encoding Cys26-Ser462 is expressed with a 6His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	12496
UniProt ID	O55026
Summary	CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by preferentially converting ATP to ADP. CD39L1 plays a role in regulating thrombosis and inflammation which is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. Alternative splicing of CD39L1 gene results in multiple transcript variants.

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