IFNW1 (22-195, His-Tag) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) LGCDLPQNHG LLSRNTLVLL HQMRRISPFL CLKDRRDFRF PQEMVKGSQL QKAHVMSVLH EMLQQIFSLF HTERSSAAWN MTLLDQLHTG LHQQLQHLET CLLQVVGEGE SAGAISSPAL TLRRYFQGIR VYLKEKKYSD CAWEVVRMEI MKSLFLSTNM QERLRSKDRD LGSS
Tag	His-Tag
Predicted MW	20.9kDa (180aa)
Concentration	1mg/ml (determined by Absorbance at 280nm)
Purity	> 95% by SDS-PAGE
Buffer	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Applications	SDS-PAGE, Bioactivity
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Bioactivity	Measured in a cytotoxicity assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.07 ng/ml.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Reference Data
RefSeq	NP_002168.1
Summary	IFN-omega, also known as interferon-omega, is a member of a family of proteins with antiviral, growth inhibitory and immunomodulatory activity. Type I IFNs consist of IFN alpha, beta, tau, and omega and bind to the type I IFN receptor, whereas IFN-gamma is the only type II IFN and is specific for the type II IFN receptor. IFN-omega is produced primarily in leukocytes in response to viral infection, and it has biological activities. Also, it was reported that IFN-omega could inhibit the growth of human tumors in vivo. Recombinant human IFN-omega, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

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