POLDIP1 (KCTD13) (NM_178863) Human Recombinant Protein

CAT#: TP761863

Purified recombinant protein of Human potassium channel tetramerisation domain containing 13 (KCTD13), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug



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CNY 2,040.00


货期*
2周

规格
    • 50 ug

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经常一起买 (1)
KCTD13 mouse monoclonal antibody, clone OTI3B12 (formerly 3B12)
    • 100 ul

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length KCTD13
Tag N-GST and C-His
Predicted MW 64.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_849194
Locus ID 253980
UniProt ID Q8WZ19
Refseq Size 1745
Cytogenetics 16p11.2
Refseq ORF 987
Synonyms BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Families Ion Channels: Other, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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